Projects

     
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ANTICIPATE – ANTICIPATE: extended-range multi-hazard predictions and early warnings
ANTICIPATE: dlhodobé (rozšírené) predpovede viacerých typov rizík a včasné varovania
Program: COST
Project ID: CA24144
Duration: 29.10.2025 – 28.10.2029
Project leader: Ing. Košta Radoslav
Annotation: Operational extreme weather forecasts and early warnings are generally limited to timescales of up to around 10 days and to predicting single events, such as flooding or a heatwave. However, a new generation of experimental ‘extended-range’ weather predictions that extend up to 46 days have been developed over the last decade by the world’s leading meteorological centres. A key motivation of exploring this prediction timescale is to bridge the gap between timescales, incorporate the latest ‘multi-hazard’ approaches, and improve early warnings and anticipatory actions. Currently, however, the extended-range prediction and the multi-hazard communities are largely disconnected. To date, there has been no coordinated effort to build a network that connects these disciplines and communities towards the development of operational systems. However, it is essential that these communities come together to explore windows of opportunity and instigate a step-change in the way forecasts are designed, produced and used. To address this challenge, ANTICIPATE will create the first pan-European network focused on extended-range multi-hazard predictions and warnings. ANTICIPATE will bring together existing but largely disconnected disciplines, operational practitioners and stakeholders (including extreme weather forecasting, extended-range prediction and climate dynamics, disaster risk reduction, multi-hazards, and communications) to drive forward advancements in the science, training, communication and application that will support next generation of effective early warnings that enable preparedness and action across hazards and forecasting lead times. ANTICIPATE will provide vital leadership in multi-hazard predictions and warnings, address gaps and challenges, and educate the next generation of forecasters and communicators for societal benefit.
Project website: https://www.cost.eu/actions/CA24144/
PREMEDICARE – Precision Medicine for Cardiac Arrest
Presná medicína pri zástave srdca
Program: COST
Project ID: CA24142 PREMEDICARE
Duration: 13.10.2025 – 12.10.2029
Project leader: Ing. Švehlíková Jana, PhD.
Annotation: Out of hospital cardiac arrest (OHCA) is a major health problem occurring in individuals of all sexes, ethnicities, and socioeconomic positions. OHCA is responsible for approximately one third of deaths in people aged under 50 years, yet our understanding of OHCA in this age group is sparse. Evidence suggests that inherited cardiac diseases underlie a significant proportion of OHCA cases in younger people, but we do not fully know the distribution of causes of OHCA which makes treatment and management of OHCA victims challenging. The PREMEDICARE Action brings together a multi-disciplinary group of experts to better understand the causes of OHCA and its long-term effects with the aim of facilitating the development and adoption of precision medicine strategies to alleviate the burden of OHCA in people under 50-years throughout Europe. Members of the PREMEDICARE network will work together to develop standardised procedures for better recording of data to enable identification of at-risk individuals across Europe, better understand geographical differences in the treatment of young OHCA patients and facilitate better management of long-term limitations linked to OHCA survival. The ultimate goal of the Action is to establish the tools and resources necessary to support the uptake and use of precision medicine approaches for the treatment and management of OHCA in the clinic.
Project website: https://www.cost.eu/actions/CA24142
STOCHASTICA – Stochastic Differential Equations: Computation, Inference, Applications
Stochastické diferenciálne rovnice: výpočty, inferencia, aplikácie
Program: COST
Project ID: CA24104
Duration: 26.9.2025 – 25.9.2029
Project leader: MSc. Krakovská Hana
Annotation: Stochastic differential equations (SDEs) are used to model phenomena under the influence of random noise and uncertainty and are useful in an extraordinary range of applications. In health, SDE models of tumour growth can help medical practitioners design interventions. In clean energy, they can model airflow around wind turbine blades, and enable multiscale modelling of entire wind farms and energy grids by representing small scale effects as noise. In computing, SDEs can be used to develop training algorithms for deep learning algorithms.The development and effective deployment of stochastic models requires input from a broad range of specialist experts: applied modellers, theoretical mathematicians, numerical analysts, and statisticians, all guided by the needs of stakeholders in academia and industry. However, in the current European research landscape, there is no large scale framework enabling these communities to interact, and opportunities for goal-driven research progress that is informed by all relevant expertise are being lost.Under the umbrella of computational stochastics, STOCHASTICA will bring together members of all of these communities to create a network of researchers with common goals informed by academic and industry partners. The work of the Action will generate a computational toolbox including a database of test problems, implementation guidance, and accessible descriptions of mathematical quality that empower non-specialist experts to make appropriate and routine use of stochastic models in applications such as natural resource management, renewable energy transmission, medical and public health applications including epidemiology and models of tumour growth.
Project website: https://www.ucc.ie/en/stochastica/
MEDUSSE – Seasonal-to-decadal climate predictability in the Mediterranean: process understanding and services
Sezónna až dekádová predpovedateľnosť klímy v Stredomorí: pochopenie procesov a implementácie
Program: COST
Project ID: CA23108
Duration: 8.10.2024 – 7.10.2028
Project leader: RNDr. Krakovská Anna, CSc.
Annotation: Climate forecasting has enormous potential influence in different socio-economic sectors, such as agriculture, health, water management, and energy. Actionable climate information is particularly relevant at seasonal-to-decadal timescales, where predictability is linked to slow fluctuations of the system such as those in the ocean, sea-ice and land-surface, thus bridging weather/sub-seasonal predictions (mainly relying on atmospheric initial condition) with future projections (mainly based on atmospheric radiative forcing). Seasonal-to-decadal climate forecasting has progressed considerably in recent years, but prediction skill over the Mediterranean is still limited. Better understanding the drivers of regional climate anomalies as well as exploring untapped sources of predictability constitute a much-needed and timely effort.Climate variability and change pose significant challenges to society worldwide. As a result, there is a growing demand to develop improved climate information products and outlooks to help decision making and sustainable development. This is particularly critical in the Mediterranean, a region sensible to natural hazards (e.g. droughts, floods) and vulnerable to climate stress (i.e. global warming). Such an improvement can only be achieved by coordinating efforts of research groups with different expertise and trans-disciplinary. In this Action, both the scientific challenge and societal challenge will be addressed by establishing a network of experts on climate variability, predictability, prediction and application. The Action will provide support to increase awareness and capability, and guidance to suitably evolve climate knowledge into services. Specific objectives include cross-cutting training and collaboration, empowering national hydro-meteorological agencies, and fostering a continuous communication between climate researchers and stakeholders.
Precision Neuromodulation for Chronic Pain: Integrating Functional MRI and Focused Ultrasound for Personalised Treatment
Presná neuromodulácia chronickej bolesti: Integrácia funkčnej magnetickej rezonancie a fokusovaného ultrazvuku pre personalizovanú liečbu, skratka „NeuroPain“
Program: ERANET
Project ID: NEURON_PAIN-013
Duration: 1.1.2026 – 31.8.2028
Project leader: Doc. RNDr. Witkovský Viktor, CSc.
DONUT – European Doctoral Network for Neural Prostheses and Brain Research
Európska doktorandská sieť pre neurálne protézy a výskum mozgu
Program: Horizon Europe
Duration: 1.1.2024 – 31.12.2027
Project leader: Ing. Mgr. Rosipal Roman, DrSc.
Annotation: DONUT, European Doctoral Network for Neural Prostheses and Brain Research has the mission to provide a multidisciplinary and inter-sectoral network for young talented researchers. The ambition of the project is to serve as a springboard for the expansion of EU partners into the fast-developing Brain-Computer Interface (BCI) technology and connected scientific disciplines. The DN will leverage the complementary expertise of 7 academic beneficiaries and 8 associated partners from 8 EU countries, to guide its 10 doctoral candidates (DCs) to address and solve deep problems in brain research, development of different BCI applications and systems with the latest technological advancements.The proposed DN will integrate existing research in BCI systems to make it more user-friendly, suitable for different types of potential end-users and for modern medical diagnostics. The DN would also provide excellent opportunities for career development of young researchers under the umbrella of German doctorate graduate school PK NRW (Graduate School for Applied Research in North Rhine-Westphalia, with over 180 participating professors), regularly offering specialised trainings and courses including Scientific Research Writing, Academic Presentation Skills, etc. Early scientific independence is one of key goals of training programmes.It is the ambition of DONUT to build a strong and lasting network not only between the DCs but also between the participating beneficiaries and associated partners. DONUT researchers will benefit of a dense network of contacts with scientists acquired during network-wide training events, to improve their career prospects in the European and worldwide innovation sector, having the opportunity to become scientists employable in both the industrial and academic sectors. The participation of 7 industrial participants in research and training programmes will guarantee extensive inter-sectoral experience for the trainees and maximise the impact. Project Partners:Rhine-Waal University of Applied Sciences (HSRW), GermanyRadboud University (RU), NetherlandsKatholieke Universiteit Leuven (“KU Leuven”) (KUL), BelgiumUniversidad Miguel Hernández de Elche (UMH), SpainAarhus University (AU), DenmarkKauno technologijos universitetas (KTU), LithuaniaInstitute of Measurement Science, Slovak Academy of Sciences (IMSAV), Slovakia
PhoBioS – Understanding interaction light – biological surfaces: possibility for new electronic materials and devices
Pochopenie interakcie svetlo – biologické povrchy: možnosti pre nové elektronické materiály a zariadenia
Program: COST
Project ID: COST CA 21159
Duration: 19.10.2022 – 18.10.2026
Project leader: RNDr. Hain Miroslav, PhD.
Annotation: It is known that various biological surfaces are covered with micro- and nano-structures that perform a variety of functions (e.g., anti-reflective, structural coloration, anti-fouling, pro- or anti-adhesion …) and inspire us to many industrial applications. In recent years, there has been a significant upsurge of research in this field. The main objective of the COST Action "Understanding light-biological surface interactions: opportunities for new electronic materials and devices" is to bring together scientists coming from different disciplines in this lively area of research, focusing on the photonic effects of nano- and micro-structures of biological surfaces and their bionic applications. The consortium will ensure cross-inspiration between participants coming from different research fields and foster research innovation and possible industrial development.
Project website: https://www.cost.eu/actions/CA21159/
AtheroNET – Network for implementing multiomic approaches in atherosclerotic cardiovascular disease prevention and research
Sieť/zoskupenie pre implementáciu multiomického prístupu pri prevencii a výskume aterosklerotickej choroby srdca
Program: COST
Project ID: CA21153
Duration: 17.7.2024 – 18.10.2026
Project leader: Ing. Švehlíková Jana, PhD.
Annotation: AtheroNET aims to consolidate and connect experts from different fields into European and international network that will focus on the use of multiple omics technologies and data integration through machine learning/artificial intelligence approach to bring novel paradigms in prevention, diagnosis, and treatment of atherosclerotic cardiovascular disease.
Project website: https://atheronet.eu/
DYNALIFE – Information, Coding, and Biological Function: the Dynamics of Life
Informácia, kódovanie a biologická funkcia: Dynamika života
Program: COST
Project ID: CA21169
Duration: 19.9.2022 – 18.9.2026
Project leader: RNDr. Krakovská Anna, CSc.
Annotation: In the mid-twentieth century two new scientific disciplines emerged forcefully: molecular biology and information-communication theory. At the beginning cross-fertilisation was so deep that the term genetic code was universally accepted for describing the meaning of triplets of mRNA (codons) as amino acids.However, today, such synergy has not take advantage of the vertiginous advances in the two disciplines and presents more challenges than answers. These challenges are not only of great theoretical relevance but also represent unavoidable milestones for next generation biology: from personalized genetic therapy and diagnosis, to artificial life, to the production of biologically active proteins. Moreover, the matter is intimately connected to a paradigm shift needed in theoretical biology, pioneered long time ago in Europe, and that requires combined contributions from disciplines well outside the biological realm. The use of information as a conceptual metaphor needs to be turned into quantitative and predictive models that can be tested empirically and integrated in a unified view. The successful achievement of these tasks requires a wide multidisciplinary approach, and Europe is uniquely placed to construct a world leading network to address such an endeavour. The aim of this Action is to connect involved research groups throughout Europe into a strong network that promotes innovative and high-impact multi and inter-disciplinary research and, at the same time, to develop a strong dissemination activity aimed at breaking the communication barriers between disciplines, at forming young researchers, and at bringing the field closer to a broad general audience.
ReHaB – Towards an ecologically valid symbiosis of BCI and head-mounted VR displays: focus on collaborative post-stroke neurorehabilitation
Smerovanie k spoľahlivej a uživateľsky prijateľnej symbióze BCI a VR: zameranie na kolaboratívnu neurorehabilitáciu po cievnej mozgovej príhode
Program: ERANET
Project ID: ERA-net CHIST ERA IV
Duration: 1.1.2022 – 31.12.2024
Project leader: Ing. Mgr. Rosipal Roman, DrSc.
Annotation: A growing body of evidence suggests that integrated technologies of brain-computer interfaces (BCI) and virtual reality (VR) environments provide a flexible platform for a series of neurorehabilitation therapies, including significant post-stroke motor recovery and cognitive-behavioral therapy. When immersed in such an environment, the subject\’s perceptual level of social interaction is often impaired due to the sub-optimal quality of the interface lacking the social aspect of human interactions.The project proposes a user-friendly wearable low-power smart BCI system with an ecologically valid VR environment in which both the patient and therapist collaboratively interact via their person-specific avatar representations. On the one hand, the patient voluntarily, and in a self-paced manner, manages their activity in the environment and interacts with the therapist via a BCI-driven mental imagery process. This process is computed and rendered in real-time on an energy-efficient wearable device. On the other hand, the therapist\’s unlimited motor and communication skills allow him to fully control the environment. Thus, the VR environment may be flexibly modified by the therapist allowing for different occupational therapy scenarios to be created and selected following the patient\’s recovery needs, mental states, and instantaneous responses.
The technologically undemanding of aluminate glasses with interested optical properties
Technologicky nenáročná príprava hlinitanových skiel so zaujímavými optickými vlastnosťami
Program: Open Mobility
Project ID: Open-Mob-2022-06
Duration: 1.1.2023 – 31.12.2024
Project leader: Ing. Majerová Melinda, PhD.
PARQ – Sudden cardiac arrest prediction and resuscitation network: Improving the quality of care
Predikcia náhlej srdcovej zástavy a systém resuscitácie: Zvýšenie kvality zdravotnej starostlivosti
Program: COST
Project ID: CA19137
Duration: 26.10.2020 – 25.10.2024
Project leader: Ing. Švehlíková Jana, PhD.
Annotation: Sudden cardiac arrest (SCA) causes 2 million deaths each year in Europe alone. Since SCA strikes unexpectedly and is lethal within minutes if untreated, solving this problem requires (1) recognizing individuals at risk and designing preventive strategies, (2) providing timely and effective treatment. Because SCA mostly occurs out-of-hospital, SCA victims rely on first-response treatment provided by citizens, firefighters and emergency medical services. There are large regional differences in SCA survival rates across Europe (1-30%). This suggests that regional differences in individual risk prediction, prevention and treatment have a major impact on the chance to survive. To improve survival rates across Europe it is imperative to study: 1) inherited, acquired, and environmental risk factors of SCA across European regions; 2) regional differences in preventive measures and first-response treatment strategies and their effectiveness. The PARQ Action will facilitate this research by forming a pan-European network of excellence in SCA and resuscitation science. This network includes investigators from different disciplines including cardiology, molecular biology, resuscitation science, emergency medicine, general practice and health economics. The main objectives of the Action are to promote development of standards for collection of clinical data and biological samples and to harmonize data analysis. This will aid in development of risk prediction models based on inherited, acquired and environmental risks. The PARQ action will focus on European differences in first-response treatment and develop guidelines. In summary, the PARQ Action investigators will enable breakthrough developments to decrease the incidence of SCA and improve survival, while reducing the vast regional European differences in survival rates.
Project website: https://www.cost.eu/actions/CA19137
ClinECGI – Performance Evaluation of Noninvasive Electrocardiographic lmaging for the Localization of Premature Ventricular Contraction from Clinical Data
Vyhodnotenie neinvazívneho elektrokardiografického zobrazovania pre lokalizáciu predčasnej komorovej kontrakcie z klinických dát
Program: JRP
Project ID: JRP SAV-TUBITAK 536057
Duration: 1.2.2021 – 30.6.2024
Project leader: Ing. Švehlíková Jana, PhD.
Annotation: The project is focused on advanced noninvasive methods for the localization of the origin of an undesired ventricular activity known as the extrasystoles. The treatment of these arrhythmias involves an invasive procedure using an endocardial mapping, during which such origins are eliminated by the application of radiofrequency energy. The methods proposed in the project aim to shorten this time demanding invasive procedure, by guiding the clinicians to the correct regions of the arrhythmia origin.
SP4LIFE – Smart Patch for Life Support Systems
Inteligentná náplasť pre systémy na udržanie života
Program: NATO
Project ID: NATO SPS G5825
Duration: 10.3.2021 – 10.3.2024
Project leader: doc. Ing. Tyšler Milan, CSc.
Annotation: Wearable real-time systems collecting and smartly analysing information on respiration, heartbeat, SpO2, blood pressure and body temperature could help medical personnel adopting most suitable countermeasure in case of highly stressful situations in military and civil scenarios as a result of terrorist attacks, IEDs’ or rescue operations. The system gives an alert if the health status of a person is changed to prevent overlook of critical health changes. We propose design and development of a patch-like device prototypes and methodology enabling continuous evaluation of personnel or victims’ vital parameters, using Artificial Intelligence to create software capable of real-time diagnostics and rapid countermeasures’ selection.
Project website: https://www.um.sav.sk/SP4LIFE
MU training – Measurement uncertainty training – MATHMET project to improve quality, efficiency and dissemination of measurement uncertainty training
Tréning v oblasti neistôt merania – MATHMET projekt na zlepšenie kvality, efektívnosti a šírenia zručností v oblasti analýzy neistoty výsledkov merania
Program: Multilateral – other
Project ID: MATHMET-MUT-2021
Duration: 1.10.2021 – 31.1.2024
Project leader: Doc. RNDr. Witkovský Viktor, CSc.
Annotation: Measurement uncertainty is a key quality parameter to express the reliability of measurements and an understanding of measurement uncertainty is often a precondition for advances in science, industry, health, environment, and society in general. However, there is a documented need for a better understanding of measurement uncertainty and its evaluation in many communities and recently this need was restated pointing to the importance of training on measurement uncertainty. Many metrology institutes, universities, national accreditation bodies, authorities in legal metrology, and others offer training on measurement uncertainty. They do so independently, and there is no community of teachers for exchanging expertise or to focus attention. There is no single contact point in Europe, which coordinates efforts, prioritizes needs, or provides an overview of suitable courses and material.Based on a broad consortium this project will improve the quality, efficiency, and dissemination of measurement uncertainty training. The activity will (1) develop new material for measurement uncertainty training and (2) establish an active community for those involved in measurement uncertainty training. In the EU, the European Metrology Network MATHMET is well-suited to host such an activity.
Project website: https://www.euramet.org/european-metrology-networks/mathmet/?L=0
DYNALIFE – Information, Coding, and Biological Function: the Dynamics of Life
Informácia, kódovanie a biologická funkcia:Dynamika života
Program: COST
Project ID: CA21169
Duration: 11.1.2023 – 31.12.2023
Project leader: Mgr. Chvosteková Martina, PhD.
Understanding and modeling compound climate and weather events
Porozumenie a modelovanie združených klimatických a meteorologických javov
Program: COST
Project ID: CA17109
Duration: 14.9.2018 – 12.3.2023
Project leader: Mgr. Chvosteková Martina, PhD.
Annotation: Hazards such as floods, wildfires, heatwaves, and droughts usually result from a combination of interacting physical processes that occur across multiple spatial and temporal scales. The combination of physical processes leading to an impact is referred to as a Compound Event. Examples of high-impact Compound Events include (i) droughts, heatwaves, wildfire and/or air pollution and their interactions involving a complex interplay between temperature, humidity and precipitation; (ii) extreme precipitation, river discharge and storm surge interactions, combining coastal storm processes with fluvial/pluvial and ocean dynamics; (iii) storms including clustering of major events leading to spatial and/or temporal dependence.Climate change alters many of these processes and their interaction, making projections of future hazards based on single driver analyses difficult. Impact studies considering only one driver usually fail to assess the extent of the impacts of Compound Events. It is thus not clear whether climate models can capture major changes in risk associated with Compound Events. Existing modelling approaches used to assess risk may therefore lead to serious mal-adaptation.DAMOCLES will (a) identify key process and variable combinations underpinning Compound Events; (b) describe the available statistical methods for modelling dependence in time, space, and between multiple variables; (c) identify data requirements needed to document, understand, and simulate Compound Events, and (d) propose an analysis framework to improve the assessment of Compound Events. DAMOCLES brings together climate scientists, impact modellers, statisticians, and stakeholders to better understand, describe and project Compound Events, and foresees a major breakthrough in future risk assessments.
Project website: https://www.cost.eu/actions/CA17109
European network for advancing Electromagnetic hyperthermic medical technologies.
Európska sieť pre pokrok v elektromagnetických hypertermických medicínskych technológiách
Program: COST
Project ID: COST action CA17115
Duration: 4.9.2018 – 3.3.2023
Project leader: Mgr. Teplan Michal, PhD.
Annotation: Electromagnetic (EM) hyperthermic technologies hold great potential in the treatment of diseases, especially for cancers that are resistant to standard regimens. These technologies modify tissue temperature: hyperthermia heats the diseased tissue to make it susceptible to treatments, and ablation heats the tissue until it is destroyed. Hyperthermia is particularly effective in treatment of cervical and breast cancer, head and neck cancers, sarcoma in adults, and germ cell tumours in children; while radiofrequency and microwave ablation offer promise for treating liver, kidney, and lung cancers.Overall, these techniques have shown significant potential and there is substantial opportunity to solidify their use clinically and to apply them to a wider range of medical conditions. However, underpinning the development of these techniques is the need for accurate knowledge of the dielectric and thermal properties of tissues, which provide the foundation for these technologies and de-risk the technical challenge before commercialization. Furthermore, contributing to the stagnant market of EM hyperthermic medical devices is the fact that, often researchers working on the development of medical technologies are not fully aware of, and not trained to address, the clinical and commercialisation challenges facing novel medical devices. To address these challenges, the MyWAVE Action takes a holistic approach by bringing together key players in the field of dielectric spectroscopy, translational research, and medical professionals. Conjoining these varied communities into one collaborative network is critical to advance the design, development, and commercialisation of EM hyperthermic technologies, so that they can reach patients faster and improve treatment outcomes.
Project website: www.cost.eu/actions/CA17115
COMULIS – Correlated Multimodal Imaging in Life Sciences
Korelované multimodálne zobrazovanie vo vedách o živej prírode
Program: COST
Project ID: CA 17121
Duration: 1.1.2019 – 11.10.2022
Project leader: RNDr. Hain Miroslav, PhD.
Annotation: The network aims at fueling urgently needed collaborations in the field of correlated multimodal imaging (CMI), promoting and disseminating its benefits through showcase pipelines, and paving the way for its technological advancement and implementation as a versatile tool in biological and preclinical research. CMI combines two or more imaging modalities to gather information about the same specimen. It creates a composite view of the sample with multidimensional information about its macro-, meso- and microscopic structure, dynamics, function and chemical composition. Since no single imaging technique can reveal all these details, CMI is the only way to understand biomedical processes and diseases mechanistically and holistically. CMI relies on the joint multidisciplinary expertise from biologists, physicists, chemists, clinicians and computer scientists, and depends on coordinated activities and knowledge transfer between academia and industry, and instrument developers and users. Due to its inherently multidisciplinary and cross-functional nature, an interdisciplinary network such as this Action is indispensable for the success of CMI. Nevertheless, there is currently no European network in the field. Existing scattered efforts focus on correlated light and electron microscopy or (pre)clinical hybrid imaging. This Action will consolidate these efforts, establish commonly-accepted protocols and quality standards for existing CMI approaches, identify and showcase novel CMI pipelines, bridge the gap between preclinical and biological imaging, and foster correlation software through networking, workshops and open databases. The network will raise awareness for CMI, train researchers in multimodal approaches, and work towards a scientific mindset that is enthusiastic about interdisciplinary imaging approaches in life sciences.
Project website: https://cost.eu/actions/CA17121
Novel integrated approaches for research of biomedical effects of pulsed electric fields
Nové integrované prístupy pre výskum biomedicínskych účinkov pulzných elektrických polí
Program: Inter-academic agreement
Project ID: SAV-18-11
Duration: 1.1.2018 – 31.12.2021
Project leader: Mgr. Teplan Michal, PhD.
Annotation: Intense pulsed electric fields have already use and great further potential for novel applications in biomedicine and food industry. However, the mechanistic details of the action of pulsed electric fields on the plasma membrane and especially on the intracellular level are still not clear. This project is focused on theoretical and experimental characterization of the effects of pulsed electric fields from the level of subcellular biomolecular structures to a cellular level. We aim to develop and employ approaches based on impedance spectroscopy and chemiluminescence detection which will enable us to explore the most prominent bioeffects of pulsed electric fields in a real-time, non-invasive and label-free manner. The major technological novelty will be in the integration of these monitoring tools to an automatic programmable experimental platform.The results of the project will provide new methods in the research of effects of electromagnetic fields on living cells and will bring future medical applications closer to reality.
Wearable Robots for Augmentation, Assistance or Substitution of Human Motor Functions
Nositeľné robotické zariadenia pre posilnenie, podporu alebo náhradu motorických funkcií človeka
Program: COST
Project ID: CA16116
Duration: 15.3.2017 – 14.9.2021
Project leader: Doc. Ing. Přibilová Anna, PhD.
Annotation: Wearable Robots (WRs) is an emerging field of personal devices that are integrated parts of human functioning, and that are constructed of typical robotic components such as actuators, sensors and control algorithms. Where conventional robots were typically intended for use in industrial environments to help in tedious and repetitive tasks and tasks requiring high precision, the situation is currently evolving to one where there is an increasing direct physical interaction between robot and human operator. The interaction with humans in WRs is not only physical, but also includes cognitive aspects, as in the interaction, control of functions is typically shared by human and machine. WRs can be used either to augment, train or supplement motor functions or to replace them completely. Wearable Robots operate alongside human limbs, as is the case in orthotic robots, exoskeletons or robotic suits. WRs are expected to find applications in Medical, Industrial and Consumer Domains, such as neuro-rehabilitation, worker support, or general augmentation. As WRs continuously interact with humans in multiple situations, Human Robot Interaction, Ergonomics, and Ethical, Legal and Societal (ELS) considerations, as well as early involvement of stakeholders are of essential interest. This Action focuses on the European integration of different underlying disciplines in science and engineering, as well as on engaging of stakeholders to improve WR technology and its societal impact.
Project website: https://www.cost.eu/actions/CA16116
MULTI-FORESEE – MULTI-modal Imaging of FOREnsic SciEnce Evidence (MULTI-FORESEE) – tools for Forensic Science
Multimodálne zobrazovanie dôkazov forenznej vedy – nástroje pre forenznú vedu
Program: COST
Project ID: CA16101
Duration: 1.8.2018 – 1.3.2021
Project leader: RNDr. Hain Miroslav, PhD.
Annotation: The main objective is to promote innovative, multi-informative, operationally deployable and commercially exploitable imaging solutions/technology to analyse forensic evidence. Forensic evidence includes, but not limited to, fingermarks, hair, paint, biofluids, digital evidence, fibers, documents and living individuals. Imaging technologies include optical, mass spectrometric, spectroscopic, chemical, physical and digital forensic techniques complemented by expertise in IT solutions and computational modelling. Imaging technologies enable multiple physical and chemical information to be captured in one analysis, from one \’specimen\’, with information being more easily conveyed and understood for a more rapid exploitation. The ‘enhanced’ value of the evidence gathered will be conducive to much more informed investigations and judicial decisions thus contributing to both savings to the public purse and to a speedier and stronger criminal justice system. Lack of knowledge sharing, standardised protocols and communication between Academia, End Users and industry has been a barrier to translational science in this field; the Action will use the unique networking and capacity-building capabilities provided by the COST framework to bring together their knowledge and expertise; this is paramount to engage in a synergistic approach to boost imaging technological developments, allowing scientifically sound, highly reliable and multi-informative intelligence to be provided to investigators, prosecutors and defence. COST support is crucial to conquer the challenge on short term basis and to provide a legacy to Europe to advance knowledge for the deployment of cutting edge, innovative and implementable imaging forensic science.
Project website: https://www.cost.eu/actions/CA16101
KZM – Comparative imaging methods based on magnetic resonance
Komparatívne zobrazovacie metódy na báze magnetickej rezonancie
Program: Bilateral – other
Project ID: ASC-2020
Duration: 1.3.2017 – 31.12.2020
Project leader: Prof. Ing. Frollo Ivan, DrSc.
Annotation: Research of comparative imaging methods based on magnetic resonance for diagnostics of neurological and musculoskeletal diseases.Imaging of micro- and nanostructures based on magnetic resonance for biomedical and material research.Mutual visits of scientists and PhD students enabling them to perform imaging experiments on MRI instruments in the laboratories of partners in the appropriate time limits.
Preparation and study of the precursor properties for development of nanomaterials based on metal oxides
Príprava a štúdium vlastností prekurzorov pre vývoj nanomateriálov na báze oxidov kovov
Program: Bilateral – other
Project ID: AI5/TT/1170
Duration: 1.7.2016 – 31.12.2020
Project leader: RNDr. Cigáň Alexander, CSc.
Annotation: The subject of common interest include the following main areas:1. Technology of HTc superconducting oxides based on Yttrium, Bismuth, Thalium and Mercury – bulks, tapes and thin films. 2. Investigation of the physical properties of these materials with the help of magnetization measurements. 3. Common experiments performed with LTc SQUID gradiometric system (at IMS SAS, Bratislava) and LakeShore susceptometer (at the Department of Inorganic and Physical Chemistry, Ghent). 4. Publication of results on cooperative scientific activities.
EMF-MED – European network for innovative uses of EMFs in biomedical applications
Európska sieť pre inovatívne využitie elektro-magnetických polí v biomedicínskych aplikáciach
Program: COST
Project ID: BM1309
Duration: 16.4.2014 – 15.10.2018
Project leader: Mgr. Teplan Michal, PhD.
Annotation: The Action will provide a cooperative framework to support the research on beneficial biological effects of non-ionizing electromagnetic fields (EMFs) and their use in biomedical applications. Research on biological effects of EMFs has traditionally focused on health risks. Inspired by promising recent studies on useful biomedical EMF interactions and applications, this Action will focus on beneficial effects, aiming for breakthrough results, new discoveries and innovative biomedical technologies. The Action will provide a better understanding of underlying physical and biological interaction mechanisms, related to both cancer and non-cancer applications, filling the gaps in the present state of knowledge. Ultimately, the Action will aim to contribute to development and optimization of innovative EMF-based medical devices and procedures, which will be safer, more efficient and less invasive. Interdisciplinarity of the proposed topic and significance of the expected outcomes require a concerted research network at the European level.
Project website: https://www.cost.eu/actions/BM1309
RTS-02 clock series registrar modules
Moduly registrátorov taktových sérií RTS-02
Program: Bilateral – other
Project ID: 08626319/16201274-74
Duration: 18.2.2016 – 31.12.2017
Project leader: Ing. Krušinský Dušan
Annotation: The subject of the NICA project is the development and production of computer modules for magnetic field cycle control in the NUCLOTRON accelerator and in the upcoming collider.
Exploring physical basis of electromagnetic field interactions with biomolecules, cells and tissue
Skúmanie fyzikálnych základov interakcií elektromagnetických polí s biomolekulami, bunkami a tkanivom
Program: Inter-academic agreement
Project ID: SAV-AV CR 15-22
Duration: 1.1.2015 – 31.12.2017
Project leader: Mgr. Teplan Michal, PhD.
Annotation: This project is focused on theoretical and experimental characterization of electromagnetic properties of biosystems from the level of subcellular biomolecular structures to a tissue level. The intention is to gain more information about the biological response to electromagnetic fields in a wider range of frequencies. New approaches will be developed for obtaining electromagnetic characteristics of subcellular/cellular structures and tissues with direct path to diagnostic and therapeutic applications. Methods for measurement and modelling of the biological response of various biosystems to external application of electromagnetic fields will be examine. Building of electromagnetic stimulation and monitoring system based on impedance spectroscopy will serve for investigation of electrical and other physiological properties of biosystems.
Synchronization and causality in complex systems: time series methods
Synchronizácia a kauzalita v zložitých systémoch: Metódy analýzy časových radov
Program: Inter-academic agreement
Project ID: SAV-AV ČR 15-18
Duration: 1.1.2015 – 31.12.2017
Project leader: RNDr. Krakovská Anna, CSc.
Annotation: Two fundamentally different approaches to detect interactions and direction of coupling (causality in the Granger sense) will be tested and compared using benchmark data generated by different mathematical models. Common and complementary features of the approaches will be identified and criteria for informed choice of an appropriate method for a particular application will be proposed. The acquired knowledge and developed computer algorithms based on originally advanced mathematical methods will be applied in analyses of experimental time series recording brain dynamics and climate variability.
Diagnostics of human articular cartilage using MRI
Diagnostika ľudských kĺbových chrupaviek pomocou metód MRI
Program: Bilateral – other
Duration: 1.8.2006 – 31.12.2016
Project leader: Prof. Ing. Frollo Ivan, DrSc.
Annotation:
Advanced optical methods for nanoelectronics
Pokročilé optické metódy pre nanoelektroniku
Program: Bilateral – other
Duration: 1.1.2006 – 31.12.2016
Project leader: RNDr. Hain Miroslav, PhD.
Annotation: International cooperation is covered by the Memorandum of Understanding between the Institute of Measurement Science of the Slovak Academy of Sciences and the Nanoelektronics Research Institute AIST in Tsukube, Japan.
Origins and evolution of lifer on Earth and in the Universe
Vznik a evolúcia života na Zemi a vo vesmíre
Program: COST
Project ID: TD1308
Duration: 15.5.2014 – 31.12.2016
Project leader: RNDr. Štrbák Oliver, PhD.
Annotation: This Action addresses three basic questions that fascinate and intrigue scientists, and the general public alike, questions that are pivotal to our understanding and appreciation of our place in the universe. Where, when and how did life emerge and evolve on Earth. What are the conditions under which life can exist. Does life exist elsewhere in the Universe and, if it does, how can it be detected and identified.
Project website: https://www.cost.eu/actions/TD1308
COSCH – Colour and Space in Cultural Heritage (COSCH)
Farba a priestor v kultúrnom dedičstve
Program: COST
Project ID: COST TD1201
Duration: 7.11.2012 – 6.11.2016
Project leader: RNDr. Hain Miroslav, PhD.
Annotation: Scientific contribution of the Institute of Measurement Science will be focused mainly on the field of X-ray computed microtomography devoted to the nondestructive high resolution 3D measurement, visualisation and microstructure analysis of cultural heritage artefacts, development of optical multi-spectral measurement and imaging techniques, including infrared reflectography, infrared thermography and ultraviolet fluorescence.
Project website: http://www.cosch.info
High Resolution Multiple-lead ECG measurement for model based interpretation of cardiac electrical field
Mnohokanálové merania EKG s vysokým rozlíšením na modelovo založenú interpretáciu elektrického poľa srdca
Program: Inter-academic agreement
Duration: 1.1.2013 – 31.12.2015
Project leader: doc. Ing. Tyšler Milan, CSc.
Annotation: The aim of the project is the cooperation in analysis and model-based interpretation of high resolution multi-leads ECG measurements data. This concerns the development of new methods for non-invasive diagnostics of specific cardiac insufficiencies such as ischemia and risk of ventricular arrhythmias, important in prevention of sudden cardiac death of patient after myocardial infarction. The experimental data and theoretical results of model-based interpretation of cardiac electric field will be exchanged within the project. The noninvasive high resolution ECG measurements with verification of developed new diagnostic procedures will be provided in cooperation with medical centers in both countries (Department of Cardiology, Warsaw Medical University, Warsaw, Poland and The National Institute of Cardiovascular Diseases, Bratislava, Slovakia).
Research and applications on HTc superconductors
Výskum a aplikácie VT supravodičov
Program: Inter-academic agreement
Duration: 1.11.1999 – 31.12.2015
Project leader: RNDr. Cigáň Alexander, CSc.
MPNS – European Network for Hyperpolarization Physics and Methodology in NMR and MRI
Európska sieť pre fyziku a metodológiu hyperpolarizácie v NMR a MRI
Program: COST
Project ID: TD1103
Duration: 1.7.2011 – 27.10.2015
Project leader: Prof. Ing. Frollo Ivan, DrSc.
Annotation: The project aims to stimulate and accelerate collaborations and joint research efforts between European groups into hyperpolarization physics and methodology with the goal to develop robust strategies for sensitivity enhancement in NMR and MRI. Coordinated short-term scientific missions (STSMs) will make it possible to fully exploit the potential of unique scientific instrumentation which already exists in a number of European groups. Summer schools and workshops will provide education and training for the early stage researchers that are entering the interdisciplinary research field. The scientific programme is organised into 5 different working groups that focus on key issues related to the topic of the Action. The scientific programme of this Action loading … is supported by a wide range of research groups thus generating a high added value for the European research landscape.
Project website: http://www.cost.esf.org/domains_actions/mpns/Actions/TD1103
Modern methods for evaluation of electrophysiological signals
Moderné metódy spracovania elektrofyziologických signálov
Program: Inter-academic agreement
Duration: 1.1.2012 – 31.12.2014
Project leader: Doc. RNDr. Witkovský Viktor, CSc.
Annotation: The aim of the project is interdisciplinary research combining nonlinear dynamics and mathematical statistics in the development of new approaches to the analysis of complex, especially electrophysiological, EEG-type signals. Current results of neural oscillation detection and phase synchronization studies of EEG signals in various sleep states and audiovisual stimulation have been presented at five international conferences and have been or will be published in impacted journals.
ISOPREN – Synthesis rate of isoprene in the periphery of the human body
Rýchlosť syntézy izoprénu v ľudskom tele
Program: Bilateral – other
Project ID: SK-AT-0025-12
Duration: 1.1.2013 – 31.12.2014
Project leader: Doc. RNDr. Witkovský Viktor, CSc.
Annotation: Isoprene is a by-product of cholesterol biosynthesis. It is one of the most abundant volatile compounds in exhaled breath. It can be measured in real-time, even in breath-to-breath resolution. The periphery of the human body can be depleted from isoprene by exertion of effort. Re-synthesis of isoprene and complete replenishment of the isoprene stores takes about 2h. Hence the synthesis rate of isoprene can be measured non-invasively through analysis of exhaled breath. In the present project, the isoprene concentration is modeled by a 3-compartment model, consisting of a richly perfused tissue compartment, a peripheral compartment and an alveolar compartment. Isoprene is produced and metabolized in the richly perfused tissue and the peripheral compartment. Two different methodologies will be employed to determine the synthesis rates of isoprene: – Off-line simulation using a “multiple shooting” technique for inverse parameter identification. – On-line simulation using Kalman filtering. A main focus will be on determination of the confidence intervals for the production and metabolization rate of isoprene. For the on-line simulation, we envisage a 7-dimensional Kalman state-space, consisting of the isoprene concentrations in the three compartments. A main task will be to find optimal choices of the process noise and the measurement noise, so that the convergences of the error covariance matrices is fast (in terms of the number of time steps). The project will be focused also on development of appropriate methods and algorithms forstatistical estimation of the confidence intervals for synthesis and metabolization rates. Before their application the statistical properties of the suggested procedures will be evaluated theoretically and/or by simulations. The research will be organized in the following two steps: First the off-line simulation will be performed. This will be done using a “multiple shooting” technique for inverse parameter identification. A main focus will be on determination of confidence intervals for the production rate and metabolization rate of isoprene in richly perfused tissue and in the periphery of the body. Subsequently the on-line simulation will be developed. The Austrian partner (Breath Research Unit of the Austrian Academy of Sciences) has the expertise to perform real-time measurements of isoprene in exhaled breath and the Slovak partner (Institute of Measurement Science, Slovak Academy of Sciences Bratislava) has experience with modeling and with the tools to determine the statistical uncertainty of identified parameters.
Apparatus for Nuclotron magnetic field control
Aparatúra riadenia cyklu magnetického poľa Nuklotrón
Program: Bilateral – other
Project ID: 08626319/1020110-74
Duration: 1.1.2010 – 31.3.2014
Project leader: Ing. Ondriš Ľubomír, CSc.
Annotation:
Noninvasive measurement and information analysis of bioelectric signals
Neinvazívne meranie a informačná analýza bioelektrických signálov
Program: Inter-academic agreement
Duration: 25.10.2001 – 31.12.2013
Project leader: doc. Ing. Tyšler Milan, CSc.
Annotation: The subject of common interest include the following main areas:1. Development and analysis of mathematical models of bioelectric sources of the heart, brain and other human organs for recognition of pathological events.2. Development of methods for mapping of bioelectric fields and their imaging on a standard surface enclosing the considered organ with indication of the anatomical landmarks.3. Creation of common database of measured surface potential data together with complementary geometrical and diagnostic information.4. Organization of international working groups and preparation of multilateral projects with research and clinical institutions for testing of the developed techniques, securing their methodological support and providing their widespread use as a new generation of computerized biomedical technology.5. Practical implementation of proposed methods and concepts on the basis of computerized measuring and diagnostic systems in medical clinics.6. Publication of results on cooperative scientific activities and preparation of manuals, handbooks, and other educational materials for practical application of the developed methods.
Measurement and Information Processing for Diagnostic Imaging of Cardiac and Brain Electrical Fields
Meranie a spracovanie informácií pre diagnostické zobrazovanie elektrických polí srdca a mozgu
Program: Inter-academic agreement
Duration: 1.1.2010 – 31.12.2012
Project leader: doc. Ing. Tyšler Milan, CSc.
Annotation: Research of new methods and computer-aided systems for high resolution multilead measurement and advanced model-based imaging and diagnostic interpretation of cardiac and brain electrical fields. Experimental verification of the methods with medical partners in both countries.The partners will cooperate in research that is in concordance with the current research goals of their Institutes. The main subjects of the joint project will be:• modelling of the cardiac and brain electrical fields during normal and pathologically changed function,• research of inverse model-based methods for early non-invasive identification of local repolarization changes arising from one or multiple ischemic lesions in the heart,• evaluation of cooperation degree between different regions of brain cortex and assessment of their mutual causal relations by means of phase synchronization built on discrete wavelet transform, with the aim to characterize different physiological and pathological brain states,• adaptation of the methods to individual patient’s chest or head geometry and investigation of their influence on the assessment of cardiac electrical sources or evaluation of cooperation between brain regions,• development of equipment and software systems for high resolution measurement and real-time representation and diagnostic imaging of cardiac and brain signals,• engineering and informatical support of experimental clinical measurements in both countries.
Model based analysis and diagnostic interpretation of cardiac electric field measured by high-resolution ECG
Modelovo založená analýza a interpretácia elektrického poľa srdca meraného pomocou EKG s vysokým rozlíšením
Program: Inter-academic agreement
Duration: 1.1.2010 – 31.12.2012
Project leader: doc. Ing. Tyšler Milan, CSc.
Annotation: The project is aimed at research and development of new methods for model based interpretation and multi-parameters analysis of the cardiac electrical field measured by high resolution multi-leads ECG from the torso surface. It is oriented to non-invasive early detection of cardiac hypoxia (ischemia) and risk of ventricular arrhythmias leading to sudden cardiac death of patients after myocardial infarctions. Project comprises common evaluation of theoretical results and experimental data, as well as introduction of proposed methods to collaborating medical centers in both countries (Dept. of Cardiology, Central University Hospital, Warsaw, Poland and National Institute for Cardiovascular Diseases, Bratislava, Slovakia) utilizing high resolution ECG mapping systems
Modern methods for evaluation of electrophysiological signals
Moderné metódy spracovania elektrofyziologických signálov
Program: Inter-academic agreement
Duration: 1.1.2009 – 31.12.2011
Project leader: Doc. RNDr. Witkovský Viktor, CSc.
Annotation: The main theme of the project is the continuation of the cooperation between the Institute of SAS and the Academy of Sciences of the Czech Republic in the research of new methods and algorithms for the analysis of complex, especially electrophysiological signals, which can be applied in neurophysiology, resp. cardiovascular physiology.
Research and education in the field of biomedical engineering
Výskum a vzdelávanie v oblasti biomedicínskeho inžinierstva
Program: Inter-institute agreement
Duration: 1.2.2006 – 31.8.2011
Project leader: doc. Ing. Tyšler Milan, CSc.
Annotation: no description
Centrope-tt – Development of new sensoric microsystems for precise non-invasive monitoring
Vývoj nových senzorických mikrosystémov na presné neinvazívne monitorovanie
Program: European Regional Development Fund (ERDF)
Project ID: 1CE008PE
Duration: 4.2.2011 – 4.8.2011
Project leader: doc. Ing. Tyšler Milan, CSc.
Annotation: Innovation project oriented to development of new sensoric microsystems related to space medicine and telemedicine, their firmware, algorithms and software that will make possible precise noninvasive monitoring of persons. The solution included definitions of user requirements (specification of convenient modern parameters) for the area of cardiovascular diseases – as viewed from the perspective of doctors and patients. Proposed concept was verified with a group of patients. Using the concept, proposal on a system was elaborated for telemedicine applicable in clinical conditions.
TÁMOP – Improvement and development of high-resolution ECG measurement and processing methods
Zdokonalenie a vývoj metód merania a spracovania EKG s vysokým rozlíšením
Program: Bilateral – other
Project ID: TÁMOP 4.2.2
Duration: 1.2.2011 – 31.5.2011
Project leader: doc. Ing. Tyšler Milan, CSc.
Annotation:
Improvement and development of high-resolution ECG measurement processing methods
Zlepšenie a vývoj metód na HR-EKG meranie a spracovanie
Program: Bilateral – other
Duration: 1.2.2011 – 31.5.2011
Project leader: doc. Ing. Tyšler Milan, CSc.
PHELINET – Polarized Helium Lung Imaging Network
Vytvorenie siete na aplikáciu polarizovaného hélia na zobrazovanie pľúc
Program: FP6
Project ID: 036002-2
Duration: 1.3.2007 – 28.2.2011
Project leader: Prof. Ing. Frollo Ivan, DrSc.
Annotation: PHELINET (Polarized Helium Lung Imaging Network) aims at a wide dissemination and a rapid transfer to end-users of the hyperpolarized (HP) Helium3 lung MRI technique, through pan-european training and intense cooperation of eleven academic and six industrial collaborators. It focuses on (i) the realization of the strong potential of this technique for lung diseases diagnostic and for the evaluation of therapy efficacy, (ii) the development and the finalization of improved, efficient and robust methods and tools for HP Helium3 lung MRI.
Project website: http://www.um.sav.sk/sk/oddelenie-04/vytvorenie-siete-na-aplikaciu-polarizovaneho-helia-na-zobrazovanie-pluc-phel.html
High resolution measurement and model based analysis of cardiac electric field
Meranie s vysokým rozlíšením a modelová analýza elektrického poľa srdca
Program: Inter-academic agreement
Duration: 1.1.2007 – 31.12.2009
Project leader: doc. Ing. Tyšler Milan, CSc.
Optical and magnetic methods in the elaboration and characterization of thin films of metallic oxides
Optické a magnetické metódy pre zdokonalenie a charakterizáciu tenko vrstvových kovových oxidov
Program: Inter-academic agreement
Duration: 1.1.2008 – 31.12.2009
Project leader: RNDr. Cigáň Alexander, CSc.
Research of the cardiac electric field
Výskum elektrického poľa srdca
Program: Inter-academic agreement
Duration: 1.1.2007 – 31.12.2009
Project leader: doc. Ing. Tyšler Milan, CSc.
BAMOD – Breath-gas analysis for molecular-oriented detection of minimal diseases
Analýza vydychovaných plynov pre molekulárne orientovanú detekciu zriedkavých chorôb
Program: FP6
Project ID: 019031
Duration: 1.2.2006 – 31.1.2009
Project leader: Doc. RNDr. Witkovský Viktor, CSc.
Annotation: Cancer is one of the leading causes of death in Europe and the western world. At present, diagnosis of cancer very often happens late in the course of the disease since available diagnostic methods are not sufficiently sensitive and specific. An early diagnosis of cancer would improve prognosis and treatment and could save thousands of lives a year.There is strong evidence to suggest that particular cancers can be detected by molecular analysis of exhaled air. Breath analysis represents a new diagnostic technique that is without risk for the patient even if repeated frequently and can provide information beyond conventional analysis of blood and urine. Recent results suggest that detection of different kinds of cancer is possible by means of breath analysis in very early stages of the disease.This project is focused on the diagnosis of minimal disease and early stages of lung and oesophageal cancer. The analytical techniques will be gas chromatography with mass spectrometric detection (GC-MS), proton transfer reaction mass spectrometry (PTR-MS), selected ion flow tube mass spectrometry (SIFT-MS), laser spectrometry and ion mobility spectrometry (IMS).In order to establish a reliable clinical method for the diagnosis of minimal residual cancer diseases clinical expertise, basic research and technical development is necessary. The European consortium set up for this proposal represents exquisite knowledge and skills in the field of basic and clinical research and technical development. Based on its competence, the consortium has the expertise to investigate and screen for hundreds of molecules in the exhaled breath and the statistical tools to identify specific cancer markers.The objectives of the project are the development of * sensitive and specific markers sets for the detection of early cancer stages based on human breath, * reliable analytical methods to determine these markers in the clinical environment, * easy-to-use and non-expensive equipment establishing breath analysis as a novel cancer screening tool.The proposal is centred around 5 studies: A lung cancer patient study, an oesophageal cancer study, a study of cancer cell lines, a study of immune-system related cells and a study of bacterial cell lines. The SMEs in our consortium will develop analytical methodology for subsequent use in clinical applications.Workpackage "Statistical algorithms"Objectives: Development of statistical algorithms for data analysis of breath gas concentration measurements * processing of non-normal distributions of measurement results (higher-order moments and different variances may play a role), performing multiple comparisons (corresponding to different cancer stages and different control groups), * establishment of typical patterns in high-dimensional phase spaces (due to consideration of many different substances), establishment of (possibly nonlinear) projection methods from high-dimensional phase spaces to 2- or 3-dim subspaces for visualization.
Project website: http://eu-proposal.voc-research.at
Modern methods for evaluation of electrophysiological signals
Moderné metódy spracovania elektrofyziologických signálov
Program: Inter-academic agreement
Duration: 1.1.2006 – 31.12.2008
Project leader: Doc. RNDr. Witkovský Viktor, CSc.
Annotation: Nonlinear dynamics and statistics are two, not always fully interacting branches of science dealing with complex signal analysis. In cooperation with experts dealing with nonlinear dynamics and statistics, new approaches will be developed to analyze complex, especially electrophysiological signals, which will be applied mainly in neurophysiology and cardiovascular physiology.
Carcinoma screening based on exhaled breath
Monitorovanie karcinómu pľúc pomocou analýzy vydychovaných plynov
Program: Bilateral – other
Project ID: SK-AT-00206
Duration: 1.1.2006 – 31.12.2007
Project leader: Doc. RNDr. Witkovský Viktor, CSc.
Annotation: Cancer is one of the leading causes of death in the EU and the Western world. At present, diagnosis of cancer is often very late due to the development of the disease, because the available diagnostic methods are not sufficiently sensitive and specific. The aim of the project is to investigate well-defined and theoretically optimal procedures for discrimination and classification of possible patients, using classical parametric methods, statistical non-parametric methods, methods based on general linear models, using penalizing terms in classification algorithms. The specific objectives of this project are: a) Processing of measurement results without assuming normality of distribution (higher moments and unequal dispersions can play a significant role), multiple comparisons (corresponding to different disease states and different control groups). b) Determination of typical images in the higher-dimensional phase space (caused by the inclusion of several different substances), introduction of the projection method from the higher dimensional space into the 2- to 3-dimensional space for visualization. c) Involvement of young researchers. The main objective of the project is to involve young researchers from Slovakia and Austria in scientific research linked to the EU project BAMOD.
Low-Field NMR – Low-field magnetic resonance imaging (MRI) for medical applications
Zobrazovanie na báze nukleárnej magnetickej rezonancie pri nízkom magnetickom poli pre aplikácie v medicíne
Program: EUREKA
Project ID: E! 2012
Duration: 1.2.2001 – 31.1.2007
Project leader: Prof. Ing. Frollo Ivan, DrSc.
Analysis and Modelling of Cardiac Electric Field based on HR ECG Body Surface Mapping
Analýza a modelovanie elektrického poľa srdca založené na povrchovom EKG mapovaní s vysokým rozlíšením
Program: Inter-academic agreement
Duration: 1.1.2004 – 31.12.2006
Project leader: doc. Ing. Tyšler Milan, CSc.
NUKLOTRON – Development of the accelerator facility NUCLOTRON
Rozvoj urýchľovacieho komplexu NUKLOTRÓN
Program: Bilateral – other
Project ID: 03-1-0979/2005
Duration: 1.1.2005 – 31.7.2006
Project leader: Ing. Ondriš Ľubomír, CSc.
Non-destructive analysis and testing of museum objects
Nedeštruktívna analýza a testovanie muzeálnych objektov
Program: COST
Project ID: G-8
Duration: 1.1.2002 – 28.2.2006
Project leader: RNDr. Hain Miroslav, PhD.
Annotation: The COST Action aims at creating a Europe-wide network that would enable co-operation and interaction between two groups of professionals: people directly concerned with the maintenance of our cultural heritage – conservators, curators, art historians, archaeologists – and analytical scientists, including chemists, physicists, geologists, metallurgists, mineralogists and microbiologists. The main objective of the action is to improve preservation and conservation of our cultural heritage by increasing knowledge of museum objects through non-destructive analysis and testing. The scientific activities of COST G8 include organising short-term scientific missions to train scientists of both groups in the other\’s field as well as to transfer practical experience among the European countries. Regular meetings in the form of workshops are organised in order to exchange the obtained knowledge in a broader group, and six working groups are active, which allows close collaboration in a specific field.
Project website: http://srs.dl.ac.uk/arch/cost-g8/index.htm