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Selected Application Results
  • Automated Electronic System for Experiments with Stress Loadings by Hypergravitation





Automated Electronic System for Experiments with Stress Loadings by Hypergravitation

Project: Neuroendocrine function system changes during artificial microgravitational hypergravitational exposition. The project is monitored in COSPAR (Committee on Space Research).

Investigators: Frollo I., (head of the technical part of the project), Přibil J., Dermek T., Kovačič Š., Kulišov A., Gürth M (Co-operational institutes: Institute of Experimental Endocrinology SAS, Institute of Biochemistry and Genetics of Animals SAS and Institute Measurement Sciences SAV).

Applicator: Institute of Experimental Endocrinology SAS and Institute of Biochemistry and Genetics of Animals SAS.

2005-b1 Equipment serves for implementation of series of experiments on small animals that are subjected by hypokinesis or hypergravitation during different time intervals. The instrumentation is equipped by telemetric control system for programmable blood collection using cannulation from experimental animals located in hypokinetic boxes or on a centrifuge. The goal of experiments is monitoring of an influence on blood properties during different gravitational overload values G, evaluation of hormone levels, neurotransmitters and metabolism. Results serve for evaluation of living organism ability to overcome the stress load.

One set of the equipment consists of a transmitter and receiver equipped by microcomputers, 28 pairs of active rotor stepping motors, each driving two pairs of syringes. Transmitter and data signals receivers are active on frequency of 433,92 MHz using modulation ensuring high immunity towards malfunction. The equipment is controlled by computer equipped by interactive user-friendly program.

The equipment can be used also for study of microgravity effects in the animal organism during space flights for the understanding of the mechanism of the activity changes of neuroendocrine system and metabolic processes. Successful tests on animals has been performed.


  • FROLLO, I. – BANIC, B. – MRAVEC, B. - JURANI, M. – GREKSAK, M. – MACHO, L. - KVETNANSKY, R. Remote controlled equipment for multiple blood withdrawal in gravitational physiology experiments. In: Journal of Gravitational Physiology : A Journal of the International Society for Gravitational Physiology. Vol. 9, 2002, pp. 339-340.
  • KVETNANSKY, R. PETRAK, J. MRAVEC, B. JURANI, M. BARANOVSKA, M. HAPALA, I. FROLLO, I. : Effect of Hypergravity on Catecholamine Levels in Telemetrically Collected Blood of Rats During Centrifugation. 9th European Symposium on Life Sciences Research in Space and 26th Annual International Gravitational Physiology Meeting. Kolín, 2005, p61.
  • PRIBIL, J., KOVACIC, S: Optoelectric Method of Gravitation Force Measurement in Centrifuge Device. In: Proc. of the 15th International Czech-Slovak Scientific Conference RADIOELEKTRONIKA 2005. Brno, May 3-4, 2005, pp. 283-286.
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