Other International Projects:  SAV - MFA KFKI Budapest, Hungary

Duration of the project: od 1/2010- 12/2012 

Principal Investigator: doc. Ing. Milan Tyšler, CSc.

Co-operating institution: CRIP Research Institute for Material Science and Technical Physics; Hungarian Academy of Sciences; Budapes, Hungary

Research of new methods and computer-aided systems for high resolution multilead measurement and advanced model-based imaging and diagnostic interpretation of cardiac and brain electrical fields. Experimental verification of the methods with medical partners in both countries. The partners will cooperate in research that is in concordance with the current research goals of their Institutes. The main subjects of the joint project will be:

• modelling of the cardiac and brain electrical fields during normal and pathologically changed function,

• research of inverse model-based methods for early non-invasive identification of local repolarization changes arising from one or multiple ischemic lesions in the heart,

• evaluation of cooperation degree between different regions of brain cortex and assessment of their mutual causal relations by means of phase synchronization built on discrete wavelet transform, with the aim to characterize different physiological and pathological brain states,

• adaptation of the methods to individual patient's chest or head geometry and investigation of their influence on the assessment of cardiac electrical sources or evaluation of cooperation between brain regions,

• development of equipment and software systems for high resolution measurement and real-time representation and diagnostic imaging of cardiac and brain signals,

• engineering and informatical support of experimental clinical measurements in both countries.